LSIL


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  • Clinical

    • 2.5% of all paps
    • prognosis
      • many regress
      • can persist
      • 21% progress to HSIL
      • <1% progress to invasive
    • management
      • colposcopy

  • Criteria

    • nuclei 3x normal
    • mild NC ratio increase
    • variable nuclear size
    • other nuclear atypia mild
      • hyperchromatic or normal
      • uniform chromatin
        • smudgy
        • granular
        • opaque
      • irregular or smooth nuclear contour
      • nucleoli inconspicuous
    • halo (not required)
      • decent diameter
      • shap border/rim
    • binucleation common

  • Ddx

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