Kimura disease


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  • Clinical

    • East Asian
    • Head and neck subcutaneous masses and lymphadenopathy
    • 40% have salivary gland involvement
    • eosinophilia, elevated IgE

  • Histology

    • follicular hyperplasia
    • vascular germinal centers and paracortex
    • eosinophilic material (IgE) in germinal centers
    • eosinophils with microabscesses

  • Stains

    • IgE stains germinal centers

  • Ddx

    • drug related lymphadenopathy (paracortical hyperplasia)
    		•