HHV8 MCD lymphoma


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  • Name

    • large B cell lymphoma arising in HHV8 associated multicentric Castleman disease

  • Clinical

    • hx of HHV8 associated multicentric Castleman disease
    • association: HIV, Kaposi sarcoma
    • site: nodes and spleen

  • Morphology

    • sheets of infiltrating plasmablasts

  • Stains

    • positive: HHV8, cIgM with lambda restriction, LANA1
    • negative: CD79a, CD138, EBV, CD27
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