Gardner fibroma


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  • Clinical

    • age: infants-adolescents
    • size: 1-10 cm
    • associated with: Gardner syndrome, FAP, APC mutation

  • Histology

    • border: poorly circumscribed
    • collagen, haphazard arrangement
    • scattered spindle cells, small vessels
    • central cracking artifact

  • Stains

    • vimentin, CD34+
    • actin, desmin, ER/PR negative
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