Bowen disease


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  • Histology

    • full thickness atypia
    • loss of maturation

  • Variants

    • Bowen disease: more blue quality of cells
    • erythroplasia of queyrat: glans penis
    • Bowenoid papulosis: HPV related, verrucous papules in genital region
    • pigmented Bowen disease

  • Ddx

    • Paget disease
      • PASD resistant
      • CEA+
    • melanoma
    • intraepidermal porocarcinoma
    • sebaceous carcinoma
    		•