BCC


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  • Clinical

    • pearly papule on nose
    • associations: Gorlin syndrome (BCC, KCOT), Bazex syndrome, Rombo syndrome

  • Histology

    • blue islands
    • peripheral palisading
    • high NC ratio
    • clefting/retraction artifact
    • fibromyxoid stroma

  • Variants

    • superficial BCC (dips down from epidermis)
    • nodular BCC (nodular islands)
    • micronodular BCC (small islands)
    • sclerosing/morpheaform BCC (sclerotic stroma, small islands)
    • infiltrative BCC (spiky infiltration)
    • varants with spaces
      • cystic BCC
      • fibroepithelioma of Pinkus (net-like)
      • adenoid BCC (adenoid cystic spaces)
      • adamantinoid BCC
    • metatypical BCC (resembles SCC)
    • other variants
      • pigmented BCC
      • infundibulocystic BCC (pink cords with blue buds, horn cysts)
      • linear basal cell nevus (congenital, looks like BCC)
      • pleomorphic BCC
      • granular cell BCC
      • clear cell BCC
      • follicular BCC (arises from follicle)
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